Nuclear Receptor Co-Repressor 1 (NCOR1) Peptide
NCOR1
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN980538
Quick Overview for Nuclear Receptor Co-Repressor 1 (NCOR1) Peptide (ABIN980538)
Target
NCOR1
(Nuclear Receptor Co-Repressor 1 (NCOR1))
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NCOR1 antibody (Catalog #: ARP32479_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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Background
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NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
Protein Interaction Partner: CCL3,CCND2,CD82,CDKN2A,ERBB2,ESR1,ETS1,ETS2,GPS2,HDAC3,HTT,RARA,RUNX1T1,SIRT1,TBL1X,TBL1XR1,ACTN2,AR,ATXN1,BCL6,C1D,CBFA2T2,CHD1,DACH1,DDX20,DHX30,ESR1,ESR2,ETS1,ETS2,GPS2,HDAC3,HDAC5,HDAC9,HESX1,HEY2,HTT,MECP2,MYBL2,NCOR1,NR1D1,NR1D2,NR1H2,NR1H3,NR2E3,NR3C1,NR6A1,PDCD2,PHB,PML,PPARA,PPARD,PPARG,PTMA,RARA,RBPJ,RDBP,RUNX1T1,SAP30,SKI,SKIL,SP1,SPEN,TBL1X,TBL1XR1,THRA,THRB,TXNRD2,ZBTB16,ZBTB33,ZMYND11,AR,BCL6,CBFA2T3,CHD1,CLK1,CORO2A,DZIP3,ESR1,GPS2,HDAC3,HDAC4,HDAC5,HDAC7,HDAC9,HEY2,HSPA4,HTT,KDM4A,KDM5C,KIF11,MECP2,MYOD1,NCOA1,NCOR2,NFKB1,NR1D1,NR1D2,NR3C1,PDCD2,PHB,PML,PPARA,PPARD,PTMA,RARA,RARG,RDBP,REST,RUNX1T1,SAP30,SF3A1,SF3B3,SIN3A,SKI,SMARCA4,SMARCB1,SMARCC1,SMARCC2,SRCAP,TAB2,TBL1X,TBL1XR1,THRA,TRIM28,TRIM33,TXNRD2,VDR,ZBTB16,ZBTB33,ZMYND11
Protein Size: 914 -
Molecular Weight
- 104 kDa
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Gene ID
- 9611
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UniProt
- Q60974
Target
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